Electrospun PCL-Based materials for health-care applications: An overview.
Mokhena, Teboho Clement Chabalala, Mandla Brian Mapukata, Sivuyisiwe Mtibe, Asanda Hlekelele, Lerato Cele, Zamani Mochane, Mokgaotsa Jonas Ntsendwana, Bulelwa Nhlapo, Toitoi Amos Mokoena, Teboho Patrick
Mokhena, Teboho Clement
Chabalala, Mandla Brian
Mapukata, Sivuyisiwe
Mtibe, Asanda
Hlekelele, Lerato
Cele, Zamani
Mochane, Mokgaotsa Jonas
Ntsendwana, Bulelwa
Nhlapo, Toitoi Amos
Mokoena, Teboho Patrick
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Abstract
Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL-based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.
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Date
2024-01-01
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Publisher
Wiley
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Keywords
Polycaprolactone (PCL), Biomedical applications, Nanofibers